City of Hope
$500,000 Barry Rosenbloom, MD Senior Investigator Grant
Member, Board of Directors
Member, Scientific Advisory Board
Research Title: The impact of alpha catenin loss on DNA repair defects in triple negative breast cancer
Triple negative breast cancer (TNBC) is an aggressive and has a high death rate, especially in black women. We have found a gene marker that may make these tumors escape chemotherapy. Our research also shows that when this marker is not present, the tumor cells respond to a very specific type of cancer therapy. Also, there might be more immune cells that come into the tumor. Therefore, we wish to expand our research help better understand the role of this marker in breast cancer growth to improve treatment of this hard to treat form of cancer.
