Mina Nikanjam, MD, PhD
$100,000 CAREER DEVELOPMENT GRANT
Research Title: Development of a Novel dCK Inhibitor for Leukemia and Lymphoma using PET Imaging
University of California, Los Angeles
DI82 is a new potential chemotherapy drug which can kill cancer cells by preventing them from making new DNA. The project will look at drug levels in the blood, tumor, and other parts of the body using an imaging machine (PET). The drug will be tested in mice in combination with two other drugs to determine how well they work together to kill tumor cells. This information will be used in a model to predict how much drug to give patients in future human studies.