University of California, Los Angeles
$100,000 Angie and Michael David Career Development Grant
Research Title:
Cold Atmospheric Plasma for the Treatment of NF1-related Peripheral Nerve Sheath Tumors
Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft-tissue sarcomas for which the only effective therapy is surgery; NF1 patients have a greater risk of developing these tumors from plexiform neurofibromas. These tumors are collectively known as Peripheral Nerve Sheath Tumors (PNSTs). One area of active research in plasma medicine is the use of cold atmospheric plasma (CAP) in treating tumors. In this proposal, we want to investigate the role of CAP in treating NF1-related PNSTs.