
Arun Singh, MD
University of California, Los Angeles
2010
$
50000
Tower Career Development Grant
Novel immunotherapies against chemotherapy refractory ovarian cancer
When ovarian cancer stops responding to chemotherapy, few options remain for patients. One approach which may prove beneficial involves harnessing the power of the immune system to fight this disease.Our proposed treatment involves training the patient’s own immune system to selectively target their tumor cells. This targeted approach should minimize side effects and provide a long lasting, self-renewing “drug” for the patient because of the property of immune cells to reproduce themselves.In addition, we intend to use sensitive PET scans to monitor the persistence of the immune cells and their interactions with the tumor.
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